SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-hFcRn)Fcgrtem1/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00109
Research Application：cancer research,Immunotherapy,drug screening
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Strain Name：C57BL/6Smoc-Fcgrtem2(hFCGRT)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190070
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Fcgrttm3(hFCGRT)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000032
Research Application：Immunotherapy,drug screening
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Strain Name：NOD-PrkdcscidFcgrtem2(FCGRT)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200006
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Gdf15em1(hGDF15)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220151
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Strain Name：C57BL/6Smoc-H2-D1em1hHLA-A2*01Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-233927
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Strain Name：C57BL/6Smoc-Icosem1(hICOS)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00052
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Icosem2(hICOS)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190030
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：BALB/cAnSmoc-Icosem1(hICOS)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000046
Research Application：Immunotherapy,drug screening
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Strain Name：C57BL/6Smoc-Icoslem1(hICOSLG) Icosem1(hICOS)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18018
Research Application：Immunotherapy,cancer research,drug screening
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