SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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Strain Name：C57BL/6JSmo-Tnfrsf9tm2(TNFRSF9)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190077
Research Application：Immunotherapy,Cancer research,Drug screening
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Strain Name：C57BL/6JSmo-Tnfrsf9tm2(TNFRSF9)Cd3etm2(hCD3E)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210409
Research Application：Drug Screening; Immunotherapy Evaluation
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Strain Name：C57BL/6JSmo-Tnfrsf9tm2(TNFRSF9)Tnfrsf4tm1(hTNFRSF4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200272
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Strain Name：C57BL/6JSmo-Tnfrsf9tm2(h4-1BB)Pdcd1tm1(hPDCD1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200279
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Strain Name：C57BL/6JSmo-Tnfrsf9tm2(TNFRSF9)Pdcd1tm1(hPDCD1)Cd274tm1(hPD-L1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210357
Research Application：inmmue therapy；drug screening
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Strain Name：C57BL/6JSmo-Tnfsf9tm1(hTNFSF9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00048
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6JSmo-Adora2atm1(hADORA2A)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-215061
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Strain Name：C57BL/6JSmo-Albtm3(hALB)Fcgrttm2(hFCGRT)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200278
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Strain Name：C57BL/6JSmo-Cd276tm2(hB7H3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00107
Research Application：cancer research,Immunotherapy,drug screening
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Strain Name：C57BL/6JSmo-Cd276tm2(hCD276)Cd28tm2(hCD28)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210353
Research Application：inmmue therapy；drug screening
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