SMOC has developed a set of mouse models expressing humanized cytokines. These models are suitable to assess the efficacy of drugs targeting cytokines in fully immunocompetent mice.
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Strain Name：NOD.Cg-PrkdcscidIl2rgem1Tg(pCMV-hIL34-pA)1Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-220433
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Strain Name：C57BL/6Smoc-Igs2em1(pAlb-hBAFF-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-232137
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Strain Name：C57BL/6Smoc-Igs2em(pT3(b)-Kozak-hIL2 signal peptide-hIL15-Flag-polyA-pT3(b)-Kozak-hIL2 signal peptide-hIL15-Flag-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220128
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Strain Name：C57BL/6Smoc-Ccl1em2(hCCL1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000074
Research Application：Immunotherapy,drug screening
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Strain Name：C57BL/6Smoc-Ccl2em(hCCL2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-220412
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Strain Name：C57BL/6Smoc-Ccl4em1(hCCL4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210013
Research Application：drug screening
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Strain Name：C57BL/6Smoc-Clec14aem1(hCLEC14A)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-232237
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Strain Name：C57BL/6Smoc-Csf1em2(CSF1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190043
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Csf1em2(CSF1)Csf1rem3(hCSF1R)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200273
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Strain Name：BALB/cAnSmoc-Csf1em2(CSF1)Csf1rem3(hCSF1R)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220016
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