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Models

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Mice

NMG

Strain Name：NOD.Cg-PrkdcscidIl2rgem1Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-001

Prkdc and Il2rg genes were both knocked-out in NOD mice.  Lacking mature T, B and NK cells Low immune rejection against human cells and tissues Good tumorigenicity so that a small number of cells can form tumors. Significant improvement in the survival of transplanted human cells and tissues Suitable for the transplantation of human hematopoietic stem cells and the preparation of humanized mouse models Suitable as the carrier mice for the transplantation of heterologous cells and tissues

Mice

Alb-2A-DTRGFP(NMG)

Strain Name：NOD-Prkdcscid Il2rgem1Albem1(2A-DTRGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-215047

2A-DTRGFP expression cassette was knocked into the Alb gene.

Mice

B2m-KO(NMG)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1SmocB2mem1Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-002

This B2m knockout mouse model was obtained by knocking out the exon 2-3 region of mouse B2m gene on the background of NMG mouse.

Mice

hB2M-HLA A2.1(NMG,2)

Strain Name：NOD-PrkdcscidIl2rgem1B2mem1(hB2M-HLA A2.1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-225090

The endogenous mouse B2m gene was replaced by human B2M-HLA A2.1 gene.

Mice

Pten-KO

Strain Name：C57BL/6Smoc-Ptenem3Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18002

Exon5 of Pten gene was deleted to generate Pten knockout mice.

Mice

Apoe-KO(2)

Strain Name：C57BL/6Smoc-Apoeem5Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190565

Apoe-KO(2) mice (Stock No.NM-KO-190565) carry a knockout allele derived from the targeted deletion of exon 2-4. While Apoe-KO mice (Stock No.NM-KO-00033) have been pulled from shelves for some reasons.

Mice

Adh7-KO

Strain Name：C57BL/6Smoc-Adh7em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-201121

Exon 3 of Adh7 gene was deleted to generate Adh7 knockout mice.

Mice

Cav1-KO

Strain Name：C57BL/6Smoc-Cav1em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190930

Exon 3 of Cav1 gene was deleted to generate Cav1 knockout mice.

Mice

B2m-KO

Strain Name：C57BL/6Smoc-B2mem3Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18021

Exon2-3 of B2m gene were deleted to generate Ifngr1 knockout mice.

Mice

Fcgr1-KO

Strain Name：C57BL/6Smoc-Fcgr1em1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18033

The Fcgr1 knockout mouse model was obtained by knocking out all coding regions of mouse Fcgr1 gene.

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