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Mice

Plp1-Flox

Strain Name：C57BL/6Smoc-Plp1em1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-200072

These mice carry loxP sites flanking exon 3 of Plp1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Plp1 gene.

Mice

NMG

Strain Name：NOD.Cg-PrkdcscidIl2rgem1Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-001

Prkdc and Il2rg genes were both knocked-out in NOD mice. Lacking mature T, B and NK cells; Low immune rejection against human cells and tissues; Good tumorigenicity so that a small number of cells can form tumors; Significant improvement in the survival of transplanted human cells and tissues; Suitable for the transplantation of human hematopoietic stem cells and the preparation of humanized mouse models; Suitable as the carrier mice for the transplantation of heterologous cells and tissues.

Mice

CAG-hACE2-IRES-Luc-Tg

Strain Name：C57BL/6Smoc-Tgtn(CAG-human ACE2-IRES-Luciferase-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-200002

The transgene is composed of a CAG-human ACE2-IRES-Luciferase-WPRE-polyA expression cassette under the control of CAG promter.

Mice

hPD-1

Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1) /Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00015

The endogenous mouse Pdcd1 gene was replaced by human PDCD1(PD-1) gene .

Mice

hPD-L1

Strain Name：C57BL/6Smoc-Cd274em1(hPD-L1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00062

The endogenous mouse Cd274(also known as PD-L1) gene was replaced by human PD-L1 gene . While hPD-L1(2)(Stock No.NM-HU-190039) mice function similarly to hPD-L1 mice,for more detailed information please contact our technical advisor.

Mice

hACE2

Strain Name：C57BL/6Smoc-Ace2em3(hACE2-flag-Wpre-pA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200218

A human ACE2-flag-Wpre-pA expression cassette was knocked into the Ace2 gene start codon site via CRISPR/Cas9 mediated recombination.

Mice

Alb-CreERT2

Strain Name：B6.129S-Albtm1.1(CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-00002

Exons 1-7 were replaced by CreERT2 and a loxp neo casette. The KI mice have a tamoxifen-inducible cre-mediated recombination system.This strain has removed the Neo screening gene.

Mice

Kras-LSL-G12D

Strain Name：C57BL/6Smoc-Krasem4(LSL-G12D)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190003

exon2 of Kras were replaced by loxp-stop-loxp and exon2 containing G12D. When crossed with a Cre recombinase-expressing strain, this strain is useful in studies of cancer and development.

Mice

R26-CAG-LSL-RSR-tdTomato-2A-DTR

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-RSR-tdTomato-2A-DTR)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190086

These mice harbor a CAG-LSL-RSR-tdTomato-2A-DTR cassette in the Rosa26 locus generated by homologous recombination.

Mice

hCD81

Strain Name：C57BL/6Smoc-Cd81em1(CD81)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190041

The endogenous mouse Cd81 gene was replaced by human CD81 gene.

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