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Models

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Mice

Ace2-2A-CreERT2

Strain Name：C57BL/6Smoc-Ace2em2(2A-CreERT2-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200187
Validation Data：Presence

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Ace2 gene stop codon site. Ace2 encodes angiotensin I converting enzyme 2. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. This strain is useful for studying lung injury and kidney disease caused by SARS coronavirus infection.

Mice

B2m-KO(NMG)

Strain Name：M-NSG-B2memSmoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-NSG-002
Validation Data：Presence

This B2m knockout mouse model was obtained by knocking out the exon 2-3 region of mouse B2m gene on the background of NMG mouse.

Mice

hCCR4(2)

Strain Name：C57BL/6Smoc-Ccr4em1(hCCR4)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-215015

The endogenous mice Ccr4 gene was replaced by human CCR4 gene.

Mice

Acadm-repeat(E8-10)

Strain Name：C57BL/6Smoc-Acadmem1(E8-10 repeat)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200239

A E8-10 repeat cassette was knocked after exon10 of the Acadm gene.

Mice

hANGPT2

Strain Name：C57BL/6Smoc-Angpt2em1(hANGPT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200247
Validation Data：Presence

The endogenous mice Angpt2 gene was replaced by human ANGPT2 gene.

Mice

Ly6g-Cre-2A-tdTomato

Strain Name：C57BL/6Smoc-Ly6gem2(iCre-P2A-tdTomato-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200219
Validation Data：Presence

A iCre-P2A-tdTomato-polyA expression cassette was knocked into the Ly6g gene start codon site.

Mice

hCD19

Strain Name：C57BL/6Smoc-Cd19em1(hCD19) Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00110
Validation Data：Presence

The endogenous mouse Cd19 gene was replaced by human CD19 gene .

Mice

Shh-EGFP-Cre

Strain Name：C57BL/6Smoc-Shhem1(EGFP-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200232

A EGFP-iCre expression cassette was knocked into the Shh gene start codon site.

Mice

Adh7-KO

Strain Name：C57BL/6Smoc-Adh7em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-201121

Exon 3 of Adh7 gene was deleted to generate Adh7 knockout mice.

Mice

hAppNL-G-F

Strain Name：C57BL/6Smoc-Apptm3(hAppNL-G-F)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000088
Validation Data：Presence

The endogenous mouse App gene was replaced by human AppNL-G-F.

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