Rare diseases are those that affect only a small percentage of the world’s population. Most rare diseases are genetic. We provide many gene-engineered mouse models which are helpful for new therapies exploration and orphan drug development.
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                                                Mice
                                             | Strain Name:FVB-Abcb4em1Smoc 
                                                Strain State:Repository Live | Cat. NO.:NM-KO-200584                                             
                                                                                                        Disease Connection:cholecystitis, cholestasis, hepatocellular carcinoma, intrahepatic cholestasis, primary sclerosing cholangitis                                                 | |
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                                                Mice
                                             | Strain Name:C57BL/6Smoc-Abcc8em2Smoc 
                                                Strain State:Repository Live | Cat. NO.:NM-KO-225150                                             | |
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                                                Mice
                                             | Strain Name:C57BL/6Smoc-Abcd1em1Smoc 
                                                Strain State:Repository Live | Cat. NO.:NM-KO-2106014                                             
                                                                                                        Disease Connection:adrenoleukodystrophy                                                 | |
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                                                Mice
                                             | Strain Name:C57BL/6Smoc-Abcg2em1Smoc 
                                                Strain State:Repository Live | Cat. NO.:NM-KO-18013                                             
                                                                                                        Disease Connection:erythropoietic protoporphyria, hyperuricemia                                                 | |
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                                                Mice
                                             | Strain Name:C57BL/6Smoc-Abcg8em1Smoc 
                                                Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200906                                             
                                                                                                        Disease Connection:sitosterolemia                                                 | |
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                                                Mice
                                             | Strain Name:C57BL/6Smoc-Acadlem1Smoc 
                                                Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-201235                                             
                                                                                                        Disease Connection:very long chain acyl-CoA dehydrogenase deficiency                                                 | |
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                                                Mice
                                             | Strain Name:C57BL/6Smoc-Acadmem1(E8-10 repeat)Smoc 
                                                Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200239                                             
                                                                                                        Disease Connection:medium chain acyl-CoA dehydrogenase deficiency                                                 | |
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                                                Mice
                                             | Strain Name:C57BL/6Smoc-Acadvlem1Smoc 
                                                Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200908                                             
                                                                                                        Disease Connection:very long chain acyl-CoA dehydrogenase deficiency                                                 | |
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                                                Mice
                                             | Strain Name:C57BL/6Smoc-Adh7em1Smoc 
                                                Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-201121                                             
                                                                                                        Disease Connection:Parkinson's disease                                                 | |
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                                                Mice
                                             | Strain Name:C57BL/6Smoc-Agxtem1Smoc 
                                                Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-210152                                             
                                                                                                        Disease Connection:primary hyperoxaluria type 1                                                 | 
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