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Models

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Mice

hIL4-Tg(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1Tg(hIL4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-215004

These transgenic mice carry humanized IL4.

Mice

Aadacl3-KO

Strain Name：C57BL/6Smoc-Aadacl3em1Smoc
Strain State：Developing | Cat. NO.：TBD

Exon 2 of Aadacl3 gene was deleted to generate Aadacl3 knockout mice.

Mice

A3Galt2-KO

Strain Name：C57BL/6Smoc-A3Galt2em1Smoc
Strain State：Developing | Cat. NO.：TBD

Exon 2-5 of A3Galt2 gene was deleted to generate A3Galt2 knockout mice.

Mice

Aa467197-KO

Strain Name：C57BL/6Smoc-Aa467197em1Smoc
Strain State：Developing | Cat. NO.：TBD

Exon 3 of Aa467197 gene was deleted to generate Aa467197 knockout mice.

Mice

Aa465934-KO

Strain Name：C57BL/6Smoc-Aa465934em1Smoc
Strain State：Developing | Cat. NO.：TBD

Exon 1-3 of Aa465934 gene was deleted to generate Aa465934 knockout mice.

Mice

A3galt2-Flox

Strain Name：C57BL/6Smoc-A3galt2em1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of A3galt2 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of A3galt2 gene.

Mice

ICR

Strain Name：Smoc:ICR
Strain State：Repository Live | Cat. NO.：SM-006

ICR mice have good reproductive performance, strong disease resistance, a gentle temperament, and are generally used for safety evaluation, pharmacological and toxicological research, aging research, surgical experiments, and so on. They are also suitable for surrogate suckling and false pregnancy.

Mice

Aadacl4Fm1-KO

Strain Name：C57BL/6Smoc-Aadacl4Fm1em1Smoc
Strain State：Developing | Cat. NO.：TBD

Exon 2 of Aadacl4Fm1 gene was deleted to generate Aadacl4Fm1 knockout mice.

Mice

hIL2-Tg(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1Tg(hIL2)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-NSG-010

These transgenic mice carry humanized IL2.

Mice

MHCII/B2m-KO(NMG)

Strain Name：NOD.Cg-PrkdcscidIl2rgem1H2-Ab1em1H2-Aaem1H2-Eb1em1H2-Eb2em1H2-Ea-ps em1B2m em1Smoc
Strain State：Repository Live | Cat. NO.：NM-NSG-014

All sequences from the upstream of  mouse H2-Ab1 gene exon 2  to the upstream of the H2-Ea-ps gene  exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models.Also, B2m gene was knocked out. These MHC class I and II molecule-deficient mice were on the NMG genetic background and also lacked cell surface expression of both class II-A and class II-E MHC proteins and B2m of class I.

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