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Models

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Mice

hC3

Strain Name：C57BL/6Smoc-C3tm1(hC3)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000079
Validation Data：Presence

The endogenous mouse C3 gene was replaced by human C3 gene.

Mice

hCCR1

Strain Name：C57BL/6Smoc-Ccr1tm3(hCCR1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190067

The endogenous mouse Ccr1 gene was replaced by human CCR1 gene.

Mice

Mefv-hMEFV*V726A

Strain Name：C57BL/6Smoc-Mefvtm1(hMEFV-V726A)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200221

Exon 7-10 of the endogenous mouse Mefv gene was replaced by human mutation gene (exon7-10).

Mice

Tmem119-2A-tdTomato-2A-DTR

Strain Name：C57BL/6Smoc-Tmem119em1(2A-tdTomato-2A-DTR)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-210117
Validation Data：Presence

2A-tdTomato-2A-DTR expression cassette was knocked into the Tmem119 gene.

Mice

Ace2-2A-CreERT2

Strain Name：C57BL/6Smoc-Ace2em2(2A-CreERT2-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200187
Validation Data：Presence

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Ace2 gene stop codon site. Ace2 encodes angiotensin I converting enzyme 2. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. This strain is useful for studying lung injury and kidney disease caused by SARS coronavirus infection.

Mice

B2m-KO(NMG)

Strain Name：M-NSG-B2memSmoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-NSG-002
Validation Data：Presence

This B2m knockout mouse model was obtained by knocking out the exon 2-3 region of mouse B2m gene on the background of NMG mouse.

Mice

Acadm-repeat(E8-10)

Strain Name：C57BL/6Smoc-Acadmem1(E8-10 repeat)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200239

A E8-10 repeat cassette was knocked after exon10 of the Acadm gene.

Mice

hHGF(NOD-scid)

Strain Name：NOD-PrkdcscidHgftm1(hHGF)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190062
Validation Data：Presence

The endogenous mouse Hgf gene was replaced by human HGF gene.

Mice

Ly6g-Cre-2A-tdTomato

Strain Name：C57BL/6Smoc-Ly6gem2(iCre-P2A-tdTomato-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200219
Validation Data：Presence

A iCre-P2A-tdTomato-polyA expression cassette was knocked into the Ly6g gene start codon site.

Mice

Adh7-KO

Strain Name：C57BL/6Smoc-Adh7em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-201121

Exon 3 of Adh7 gene was deleted to generate Adh7 knockout mice.

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