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Models

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Mice

hB7H3/hCD28

Strain Name：C57BL/6Smoc-Cd276tm2(hCD276)Cd28tm2(hCD28)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210353
Validation Data：Presence

hB7-H3(NM-HU-00107) was crossed with hCD28(NM-HU-190011) to generate hB7H3/hCD28 mice.

Mice

hAPOC3

Strain Name：C57BL/6Smoc-Apoc3tm1(hAPOC3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-225050
Validation Data：Presence

The endogenous mouse Apoc3 gene was replaced by human APOC3 gene.

Mice

Adgre1-2A-CreERT2

Strain Name：C57BL/6Smoc-Adgre1em1(2A-CreERT2)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190025
Validation Data：Presence

A 2A-CreERT2 expression cassette was knocked into the Adgre1 gene stop codon site.

Mice

hCD28

Strain Name：C57BL/6Smoc-Cd28tm2(hCD28)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190011
Validation Data：Presence

The endogenous mouse Cd28 gene was replaced by human CD28 gene.

Mice

Shh-EGFP-Cre

Strain Name：C57BL/6Smoc-Shhem1(EGFP-iCre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200232

A EGFP-iCre expression cassette was knocked into the Shh gene start codon site.

Mice

Rag2-KO

Strain Name：C57BL/6Smoc-Rag2em2Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190429
Validation Data：Presence

Partial exon 3 of Rag2 gene was deleted to generate Rag2 knockout mice. Deletion of this region will cause frameshift and result in loss of function of mouse Rag2 gene.

Mice

Batf3-KO

Strain Name：C57BL/6Smoc-Batf3em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190447

exon 1-2 of Batf3 gene was deleted to generate Batf3 knockout mice.

Mice

hC5

Strain Name：C57BL/6Smoc-Hctm1(hC5)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000013
Validation Data：Presence

The endogenous mouse C5a gene was replaced by human C5 gene.

Mice

hCD19

Strain Name：C57BL/6Smoc-Cd19tm1(hCD19) Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00110
Validation Data：Presence

The endogenous mouse Cd19 gene was replaced by human CD19 gene .

Mice

Rag2/IL2rg-KO/hVEGFR2

Strain Name：C57BL/6Smoc-Il2rgem1Rag2em1Kdrtm2(hKDR)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220087

IL2rg-KO (NM-KO-210098) mice were crossed with Rag2-KO/hKDR (NM-HU-200280) mice to generate Rag2/IL2rg-KO/hKDR mouse models.

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