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Models

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Mice

hC5AR1

Strain Name：C57BL/6Smoc-C5ar1tm1(hC5AR1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-204989
Validation Data：Presence

The endogenous mice C5ar1 gene was replaced by human C5AR1 gene.

Mice

hCCL1

Strain Name：C57BL/6Smoc-Ccl1tm2(hCCL1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000074
Validation Data：Presence

The endogenous mouse Ccl1 gene was replaced by human CCL1 gene.

Mice

hPD-1/Cd8a-IRES-Akaluc-2A-EGFP

Strain Name：C57BL/6Smoc-Pdcd1tm1(hPDCD1)Cd8atm1(V5-IRES-Akaluc-2A-EGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210373

hPD-1(NM-HU-00015) was crossed with Cd8a-IRES-Luc-2A-EGFP(NM-KI-18030) to generate hPD-1/Cd8a-IRES-Luc-2A-EGFP mice

Mice

hCD38(2)

Strain Name：C57BL/6Smoc-Cd38tm2(CD38)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190059
Validation Data：Presence

The endogenous mouse Cd38 gene was replaced by human CD38 gene. While hCD38 mice(Stock No.NM-HU-00113）have been pulled from shelves for some reasons.

Mice

Rag2-KO

Strain Name：C57BL/6Smoc-Rag2em2Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-190429
Validation Data：Presence  |  Publications：2piece

Partial exon 3 of Rag2 gene was deleted to generate Rag2 knockout mice. Deletion of this region will cause frameshift and result in loss of function of mouse Rag2 gene.

Mice

Procr-CreERT2-2A-tdTomato

Strain Name：C57BL/6Smoc-Procrem5(CreERT2-P2A-tdtomato-Wpre-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200227

A CreERT2-P2A-tdtomato-Wpre-pA expression cassette was knocked into the Procr gene start codon site.

Mice

hC1R

Strain Name：C57BL/6Smoc-C1raem1(hC1R)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-2000075
Validation Data：Presence

The endogenous mouse C1ra gene was replaced by human C1R gene.

Mice

B2m-KO

Strain Name：C57BL/6Smoc-B2mem3Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-18021
Validation Data：Presence  |  Publications：1piece

Exon2-3 of B2m gene were deleted to generate Ifngr1 knockout mice.

Mice

Shh-EGFP-Cre

Strain Name：C57BL/6Smoc-Shhem1(EGFP-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200232
Validation Data：Presence

A EGFP-iCre expression cassette was knocked into the Shh gene start codon site.

Mice

R26-CAG-LSL-hACE2-IRES-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sortm1(SA-FRT-2xpolyA-CAG-FRT-Loxp-stop-loxp-human ACE2-IRES-tdTomato-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200188
Validation Data：Presence

These mice harbor a SA-FRT-2xpolyA-CAG-FRT-Loxp-stop-loxp-human ACE2-IRES-tdTomato-WPRE-polyAA cassette in the Rosa26 locus generated by homologous recombination.

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