Therapeutic Target-Humanized Mice
Cre/Dre-Driver Mice
Immunodeficient NMG Mice
Strain Name:C57BL/6Smoc-Oclnem1(hOCLN)Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190072
The endogenous mouse Ocln gene was replaced by human OCLN gene.
Strain Name:C57BL/6Smoc-Cd40em1(hCD40)Rag2em1Il2rgem1/Smoc Strain State:Developing | Cat. NO.:NM-HU-2000112
The Rag2 and Il2rg genes of the CD40 humanized mouse were deleted.
Strain Name:BALB/cAnSmoc-Foxp3em9(IRES-DTR-2A-tdTomato)Smoc Strain State:Repository Live | Cat. NO.:NM-KI-200213 Validation Data:Presence
A IRES-DTR-2A-tdTomato expression cassette was knocked into the Foxp3 gene stop codon site.
Strain Name:C57BL/6Smoc-Ccr2em2(hCCR2)Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-18026 Validation Data:Presence
The endogenous mouse Ccr2 gene was replaced by human CCR2 gene.
Strain Name:C57BL/6Smoc-Tnfrsf9tm2(h4-1BB)Pdcd1em1(hPDCD1)Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200279
h4-1BB(2)(NM-HU-190077) was crossed with hPD-1(NM-HU-00015)to generate h4-1BB(2)/hPD-1 mice
Strain Name:C57BL/6Smoc-Ctla4em1(hCTLA4)Cd8aem1(V5-IRES-luc-2A-EGFP)/Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210374
hCTLA4(NM-HU-00014) was crossed with Cd8a-IRES-Akaluc-2A-EGFP(NM-KI-18030) to generate hCTLA4/Cd8a-IRES-Akaluc-2A-EGFP mice.
Strain Name:C57BL/6Smoc-Cd276em2(hB7H3)Smoc Strain State:Repository Live | Cat. NO.:NM-HU-00107 Validation Data:Presence
The endogenous mouse Cd276 gene was replaced by human CD276 gene.
Strain Name:C57BL/6Smoc-Tnfrsf9em2(TNFRSF9)Cd3eem2(hCD3E)Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210409
h4-1BB(2)(NM-HU-190077) was crossed with hCD3E(2)(NM-HU-210023)to generate h4-1BB(2)/hCD3E(2) mice.
Strain Name:C57BL/6Smoc-C1s1em1(hC1S)/Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000077 Validation Data:Presence
The endogenous mouse C1s1 gene was replaced by human C1S gene.
Strain Name:C57BL/6Smoc-Kdrem2(hKDR)Rag2em1Smoc Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200280 Validation Data:Presence
The Rag2 gene of NM-HU-00098 was knock out.
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