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Models

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Mice

Alb-2A-DTRGFP(NMG)

Strain Name:NOD.Cg-PrkdcscidIl2rgem1Albem1(2A-DTRGFP)Smoc
Strain State:Developing | Cat. NO.:NM-KI-215047

2A-DTRGFP expression cassette was knocked into the Alb gene.

Mice

Cdkn2a-Luc-2A-tdTomato-2A-CreERT2(p16-Luc-2A-tdTomato-2A-CreERT2)

Strain Name:C57BL/6Smoc-Cdkn2aem(Luc-tdTomato-CreERT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-18039
Validation Data:Presence  |  Publications:1piece

A Luc-2A-tdTomato-2A-CreERT2-WPRE-pA cassette was fused in-frame with exon2 of p16INK4a transcript such that the exogenous proteins would be translated followed by the first 62aa of Cdkn2a.

Mice

hANGPTL3(4)

Strain Name:C57BL/6Smoc-Angptl3tm1(hANGPTL3)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210036
Validation Data:Presence

The endogenous mice Angptl3 gene was replaced by human ANGPTL3 gene. While hANGPTL3(Stock No.NM-HU-200113) have been pulled from shelves for some reasons and hANGPTL3(3)(Stock No.NM-HU-210037) mice function similarly to hANGPTL3(2) mice, for more detailed information please contact our technical advisor.

Mice

Rag2/IL2rg-KO/hCD40

Strain Name:C57BL/6Smoc-Cd40tm1(hCD40)Rag2em1Il2rgem1Smoc
Strain State:Developing | Cat. NO.:NM-HU-2000112

The Rag2 and Il2rg genes of the CD40 humanized mouse were deleted.

Mice

hOCLN

Strain Name:C57BL/6Smoc-Oclntm1(hOCLN)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190072

The endogenous mouse Ocln gene was replaced by human OCLN gene.

Mice

hCCR2

Strain Name:C57BL/6Smoc-Ccr2tm2(hCCR2)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-18026
Validation Data:Presence

The endogenous mouse Ccr2 gene was replaced by human CCR2 gene.

Mice

Foxp3-IRES-DTR-2A-tdTomato(BALB/c)

Strain Name:BALB/cAnSmoc-Foxp3em9(IRES-DTR-2A-tdTomato)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200213
Validation Data:Presence

A IRES-DTR-2A-tdTomato expression cassette was knocked into the Foxp3 gene stop codon site.

Mice

hB7H3

Strain Name:C57BL/6Smoc-Cd276tm2(hB7H3)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00107
Validation Data:Presence

The endogenous mouse Cd276 gene was replaced by human CD276 gene.

Mice

h4-1BB(2)/hPD-1

Strain Name:C57BL/6Smoc-Tnfrsf9tm2(h4-1BB)Pdcd1tm1(hPDCD1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200279

h4-1BB(2)(NM-HU-190077) was crossed with hPD-1(NM-HU-00015)to generate h4-1BB(2)/hPD-1 mice

Mice

h4-1BB(2)/hCD3E(2)

Strain Name:C57BL/6Smoc-Tnfrsf9tm2(TNFRSF9)Cd3etm2(hCD3E)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210409

h4-1BB(2)(NM-HU-190077) was crossed with hCD3E(2)(NM-HU-210023)to generate h4-1BB(2)/hCD3E(2) mice.

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