Models

Cytokines

SMOC has developed a set of mouse models expressing humanized cytokines. These models are suitable to assess the efficacy of drugs targeting cytokines in fully immunocompetent mice. 

Mice
Strain Name:NOD-PrkdcscidIl2rgem1Gt(ROSA)26Sorem1(SA-LSL-hCSF3)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-232692
Mice
Strain Name:C57BL/6Smoc-Cxcl13tm1(hCXCL13)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-225079
Mice
Strain Name:C57BL/6Smoc-Gdf15em(hGDF15)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-215002
Mice
Strain Name:C57BL/6Smoc-Tnfrsf18em1(hTNFRSF18)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-233216
Mice
Strain Name:C57BL/6Smoc-Hgfem1(hHGF)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200235
Mice
Strain Name:C57BL/6Smoc-Ifna1em(hIFNA1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220356
Mice
Strain Name:C57BL/6Smoc-Ifngtm(hIFNG)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220358
Mice
Strain Name:C57BL/6Smoc-Tg(hIL-8)1Smoc
Strain State:Repository Live | Cat. NO.:NM-TG-225012
Mice
Strain Name:C57BL/6Smoc-Il10tm4(hIL10)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000063
Research Application:Cytokine humanization model;drug screening
Mice
Strain Name:C57BL/6Smoc-Il11em1(hIL11)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-204981
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