hGITR(3)

Nomenclature

C57BL/6Smoc-Tnfrsf18em1(hTNFRSF18)Smoc

Cat. NO.

NM-HU-233216

Strain State

Repository Live

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Model Description

The endogenous mouse Tnfrsf18 gene was replaced by human TNFRSF18 gene.

Validation Data

image.png

Fig.1 Detection of GITR expression in thymus by RT-PCR. 

Wild type: only one band at 325 bp with primers F1/R1(mGitr);

Homozygous: only one band at 205 bp with primers F2/R2(hGITR).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of hGITR expression on Treg in Spleen in hGITR KI mice.

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