iPSC-mediated Disease Models

Introduction

The SMOC iPSC disease research model platform is based on extensive experience in cultivating stem cells and employing stem editing technology. A stable IPSC induction system has been established to ensure high efficiency in disease research models.
Benefits of iPSC in vitro disease model
  • 精准定向分化能力

    Accurate directional differential ability

    Substitute the hard-to-acquire original cells from patients

  • 高效大量扩增细胞

    Efficiently amplifying a large number of cells

    Capable of extensive drug screening efficiency within a short period

  • 支持多种基因编辑

    Support multiple gene editing

    Collaborate efficiently with disease treatment methods

Services
  • just need to provide fibroblasts/HBMC
  • additional carrier/Sendal virus (SeV) construction
  • Multidimensional stem cells feature quality control
  • Delivery 2 clones of iPSC
  • 10-14 weeks only
  • multiple types of gene editing
  • Professional gene editing technology
  • efficient screening of monoclonal cell lines
  • delivery of 2 monoclonal cell lines and 1 iPSC wild type
  • Gene knockout iPSC can be produced as fast as 8 weeks

Case Studies

Case Studies of iPSC Ex Vivo Disease Modeling Services

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Fig1. Diagram showing the process of iPS induction.


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Fig2. Service Cases of iPSC reprogramming.


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Fig3. NANOG-tdTomato knock-in iPSC line.


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Fig4. LRRK2(G2019S) point mutation iPSC line.


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Fig5. CISH knockout iPSC line.

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