Cell Line Customization Services

he SMOC Cell Line Construction Platform, led by a team of multiple experienced experts with many years of extensive experience in gene editing, offers a wide range of customized cell line services, including gene knockout, precise knock-in, overexpression, and point mutation.

项目类型

项目类型 Delivery Standards QC Timeline
Knockout 2 monoclonal gene knockout homozygous cell lines (1 vial/clonal, 10^6 cells/vial), along with an experimental report、experimental report PCR、sequencing 8-16weeks
Knockin 2 monoclonal gene knock-in heterozygous cell lines (1 vial/clonal, 10^6 cells/vial), along with an experimental report、experimental report PCR、sequencing 12-16weeks
Over expression 2 monoclonal gene overexpression positive cell lines (1 vial/clonal, 10^6 cells/vial), along with an experimental report、experimental report PCR、sequencing
qPCR、WB、FACS(optional)
12-16weeks
Point mutation In vitro Pharmacodynamic Evaluation Service provides related cell experimental services such as cell viability testing, ADCC/TDCC assays, mixed lymphocyte reaction (MLR) assays, complement-dependent cytotoxicity (CDC) assays, and antibody-drug conjugate (ADC) bystander assays.、experimental report PCR、sequencing 12-16weeks

*Actual delivery standards and timelines will depend on the complexity of the specific project, the difficulty of cell transfection and the availability of cell stocks.

Services process

  • Project Design

  • Molecular Loading Construction of Lentivirus

  • Lentivirus Titre Detection

  • Acquisition of Cell Pool

  • Monoclonal Cell Line

  • QC Identification Stability Testing

Case Studies of Cell Line Customization

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Fig1. Establish of Hela-HIST1H1C-mtagBFP2/TUBB-mNeonGreen cell line.


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Fig1. Establish of MC38-Ccl5 cell line.

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