SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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Strain Name：C57BL/6Smoc-Ctla4em1(hCTLA4) Tnfrsf9em1(hTNFRSF9) /Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18020
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Ctla4em1(hCTLA4)Cd8aem1(V5-IRES-luc-2A-EGFP)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210374
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Strain Name：C57BL/6Smoc-Ctla4em1(hCTLA4)Tnfrsf9tm2(TNFRSF9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210355
Research Application：inmmue therapy；drug screening
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Strain Name：BALB/cAnSmoc-Ccr8em1(hCCR8)Ctla4em1(hCTLA4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220050
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Strain Name：BALB/cAnSmoc-Ctla4em1(hCTLA4)Cd28em1(hCD28)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-200226
Research Application：Immunotherapy
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Strain Name：C57BL/6Smoc-Ctla4em1(hCTLA4) Il2ratm1(hIL2RA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-233159
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Strain Name：C57BL/6Smoc-Ctla4em1(hCTLA4)Tigitem1(hTIGIT)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210399
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Strain Name：C57BL/6Smoc-Fcgr2bem2(FCGR2B)Tnfrsf9tm2(TNFRSF9)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210352
Research Application：inmmue therapy；drug screening
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Strain Name：C57BL/6Smoc-Fcgr2Bem1(hFCGR2B)Cd40em1(hCD40)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200262
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Strain Name：C57BL/6Smoc-Fcgrt2Bem2(hFCGRT2B)Tnfrsf4em1(hTNFRSF4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200265
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