Abcb1a/Abcb1b-KO(SD)
Nomenclature
SD-Abcb1aemAbcb1bem1Smoc
Cat. NO.
NR-KO-241992
Strain State
Repository Live
Gene Summary
Gene Symbol
Abcb1a
Model Description
The exon 4 of Abcb1a and exon 4 of Abcb1b genes were deleted to generate Abcb1a and Abcb1b knockout rat.
*Literature published using this strain should indicate: Abcb1a/Abcb1b-KO(SD) rats (Cat. NO. NR-KO-241992) were purchased from Shanghai Model Organisms Center, Inc..
Validation Data
Fig.1 Detection of ABCB1 expression in Abcb1a/Abcb1b-KO(SD) rat by WB. Rat ABCB1 was exclusively detectable in small intestine, brain and kidney from WT SD. The small intestine, brain and kidney tissue lysates were collected from 20-week-old male wild-type SD rat and 20-week-old male homozygous Abcb1a/Abcb1b-KO(SD) rat, and then analyzed by western blot.
Abbr. HO, homozygous; WT, wild type; PC, positive control, PC1, HepG2 cells, PC2, Hela cells.
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