Tagln-Cre(SD)
Nomenclature
SD-Taglnem1(Cre)Smoc
Cat. NO.
NR-KI-210134
Strain State
Repository Live
Gene Summary
Gene Symbol
Tagln
Model Description
Cre expression cassette was knocked into the Tagln gene .
*Literature published using this strain should indicate: Tagln-Cre(SD) rats (Cat. NO. NR-KI-210134) were purchased from Shanghai Model Organisms Center, Inc..
Validation Data
Fig 1. Cre-mediated recombination in aorta of TaglnCre/+; Rosa26mTmG/+ rat.
Fig 2. Detection of tdTomato (red) and EGFP (Green) in various tissues of TaglnCre/+; Rosa26mTmG/+ rat. Expression tissues include: aorta, lung, liver, stomach, salivary gland, pituitary gland, kidney, colon, small intestine, spleen, epididymis, testis, thymus, adrenal gland. A few cells expressed in spinal cord, eyeball, heart, brown fat, pancreas, muscle. (28-day old, male) (For more detailed information please contact our technical advisor.)
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Cre-ERT2在无Tamoxifen诱导的情况下，在细胞质内处于无活性状态；当Tamoxifen诱导后，Tamoxifen的代谢产物4-OHT（雌激素类似物）与ERT结合，可使Cre-ERT2进核发挥Cre重组酶活性。
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