Humanized Metabolic Pharmacodynamics Research Model

Humanized metabolic pharmacodynamics research models are mouse models generated by inserting human metabolic-related genes or protein targets into the mouse genome using gene editing technology. These models have significant application value in the research and development of metabolic drugs.
Popular Humanized Models for Metabolic Pharmacodynamics Research
hGLP1R
hGLP1R
hGIPR
hGIPR
hINHBE
hINHBE
hANGPTL3
hANGPTL3
More Humanized Models for Metabolic Pharmacodynamics Research
Cat. NO. Strain name Specimen Name Strain State
NM-HU-233622 hGPR146 C57BL/6JSmo-Gpr146tm1(hGPR146)Smoc Repository Live
NM-HU-215056 hGPR75 C57BL/6JSmo-Gpr75tm1(hGPR75)Smoc Embryo cryopreservation
NM-HU-220417 hGUCY2C C57BL/6JSmo-Gucy2ctm(hGUCY2C)Smoc Embryo cryopreservation
NM-HU-231907 hHAO1(3) C57BL/6JSmo-Hao1tm1(hHAO1)Smoc Embryo cryopreservation
NM-HU-233512 hINHBE C57BL/6JSmo-Inhbetm1(hINHBE)Smoc Repository Live
NM-HU-230148 hLDLR C57BL/6JSmo-Ldlrtm1(hLDLR)Smoc Sperm cryopreservation
NM-HU-233876 hMC4R C57BL/6JSmo-Mc4rtm1(hMC4R)Smoc Embryo cryopreservation
NM-HU-233884 hMC4R-R165W C57BL/6JSmo-Mc4rtm1(hMC4R-R165W)Smoc Repository Live
NM-HU-200253 hNR1I3 C57BL/6JSmo-Nr1i3tm2(hNR1I3)Smoc Embryo cryopreservation
NM-HU-00075 hPCSK9 C57BL/6JSmo-Pcsk9tm2(hPCSK9)/Smoc Repository Live
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