Humanized Metabolic Pharmacodynamics Research Model

Humanized metabolic pharmacodynamics research models are mouse models generated by inserting human metabolic-related genes or protein targets into the mouse genome using gene editing technology. These models have significant application value in the research and development of metabolic drugs.
Popular Humanized Models for Metabolic Pharmacodynamics Research
hGLP1R
hGLP1R
hGIPR
hGIPR
hINHBE
hINHBE
hANGPTL3
hANGPTL3
More Humanized Models for Metabolic Pharmacodynamics Research
Cat. NO. Strain name Specimen Name Strain State
NM-KI-231910 H11-pAlb-hHAO1 C57BL/6JSmo-Igs2tm1(pAlb-hHAO1 CDS-hHAO1 3'UTR-pA)Smoc Embryo cryopreservation
NM-HU-200003 hALB C57BL/6JSmo-Albtm3(ALB)Smoc Embryo cryopreservation
NM-HU-210037 hANGPTL3(3) C57BL/6JSmo-Angptl3tm2(hANGPTL3)Smoc Sperm cryopreservation
NM-HU-210036 hANGPTL3(4) C57BL/6JSmo-Angptl3tm1(hANGPTL3)Smoc Repository Live
NM-HU-230099 hANGPTL8 C57BL/6JSmo-Angptl8tm(hANGPTL8)Smoc Repository Live
NM-HU-231781 hAPOB(2) C57BL/6JSmo-Apobtm2(hAPOB)Smoc Embryo cryopreservation
NM-HU-225050 hAPOC3 C57BL/6JSmo-Apoc3tm1(hAPOC3)Smoc Repository Live
NM-HU-190013 hAPOE2 C57BL/6JSmo-Apoetm4(hAPOE2)Smoc Repository Live
NM-HU-190003 hAPOE3 C57BL/6JSmo-Apoetm3(hAPOE3)Smoc Repository Live
NM-HU-190002 hAPOE4 C57BL/6JSmo-Apoetm2(hAPOE4)Smoc Repository Live
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