Humanized Metabolic Pharmacodynamics Research Model

Humanized metabolic pharmacodynamics research models are mouse models generated by inserting human metabolic-related genes or protein targets into the mouse genome using gene editing technology. These models have significant application value in the research and development of metabolic drugs.
Popular Humanized Models for Metabolic Pharmacodynamics Research
hGLP1R
hGLP1R
hGIPR
hGIPR
hINHBE
hINHBE
hANGPTL3
hANGPTL3
More Humanized Models for Metabolic Pharmacodynamics Research
Cat. NO. Strain name Specimen Name Strain State
NM-HU-230044 hRAMP2 C57BL/6JSmo-Ramp2tm(hRAMP2)Smoc Embryo cryopreservation
NM-HU-230045 hRAMP3 C57BL/6JSmo-Ramp3tm(hRAMP3)Smoc Embryo cryopreservation
NM-HU-220370 hREN(2) C57BL/6JSmo-Ren1tm1(hREN)Smoc Sperm cryopreservation
NM-HU-232854 hSCAP C57BL/6JSmo-Scaptm1(hSCAP)Smoc Embryo cryopreservation
NM-HU-225087 hTTR C57BL/6JSmo-Ttrtm1(hTTR)Smoc Embryo cryopreservation
NM-HU-220587 hTTR-V30M(p.V50M) C57BL/6JSmo-Ttrtm(hTTR-V50M)Smoc Embryo cryopreservation
NM-KI-200221 Mefv-hMEFV*V726A C57BL/6JSmo-Mefvtm1(hMEFV-V726A)Smoc Sperm cryopreservation
NM-TG-225001 pAlb-hLPA-Tg C57BL/6JSmo-Tg(pAlb-hLPA)1Smoc Repository Live
NM-TG-231782 pAlb-hLPA-Tg(V2) C57BL/6JSmo-Tgtn(pAlb-hLPA-3’UTR-pA)1Smoc Repository Live
NM-TG-232196 pAlb-hLPA-Tg(V3) C57BL/6JSmo-Tg(pAlb-hLPA-WPRE-pA)1Smoc Sperm cryopreservation
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