hSCAP

Nomenclature

C57BL/6Smoc-Scaptm1(hSCAP)Smoc

Cat. NO.

NM-HU-232854

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Scap

Model Description

The endogenous mouse Scap gene was replaced by human SCAP gene.

Validation Data

image.png

Fig.1 Detection of SCAP expression in ovary by RT-PCR. 

Wild type: only one band at 229 bp with primers F1/R1(mScap);

Homozygous: only one band at 191 bp with primers F2/R2(hSCAP).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human SCAP expression in hSCAP knockin mice by WB. 

Abbr. M, marker; WT, wild type; HO, Homozygous;PC, hela cells.

Note. The anti-human SCAP Antibody cross-reacted with mouse SCAP and humanized SCAP. 


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