hAPOE3
Nomenclature
C57BL/6JSmo-Apoetm3(hAPOE3)Smoc
Cat. NO.
NM-HU-190003
Strain State
Repository Live
Gene Summary
Gene Symbol
Apoe
Model Description
This APOE3 humanized mouse model was established by replacing the mouse Apoe gene coding exons and introns with the human APOE3 corresponding sequence by homologous recombination.
Research Application：Cardiovascular disease
*Literature published using this strain should indicate: hAPOE3 mice (Cat. NO. NM-HU-190003) were purchased from Shanghai Model Organisms Center, Inc..
Validation Data
Validation data
Fig1. Genotyping of WT 、KO & Humanized mice by PCR.
Primer P1/2 Wild type = 342 bp
Primer P3/4 mutant = 332 bp
M：100bp Plus DNA ladder.
Fig2. Western blot analysis of APOE3 protein from WT、KO & Humanized mice.
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