hAPLN

Nomenclature

C57BL/6JSmo-Aplntm1(hAPLN)Smoc

Cat. NO.

NM-HU-242253

Strain State

Repository Live

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Gene Summary

Gene Symbol
Apln

Model Description

The endogenous mouse Apln gene was replaced by human APLN gene.

Validation Data

image.png

Fig.1 Detection of human APLN expression in heart and lung homogenate of WT C57BL/6 mice and HO hAPLN mice by ELISA. Lysates of heart and lung tissues were collected from wild-type C57BL/6 mice (n=2 male or 2 female, 10 or 13 weeks old) and HO hAPLN mice (n=2 male or 2 female, 13 weeks old), and analyzed by ELISA with anti-hAPLN ELISA kit. APLN was detectable in heart and lung homogenate from both WT C57BL/6 and HO hAPLN mice, as the ELISA kit was cross-reactived between human and mouse APLN protein.

Abbr.  HO, homozygous; WT, wild type.


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