hPGLYRP1
Nomenclature
C57BL/6JSmo-Pglyrp1tm1(hPGLYRP1)Smoc
Cat. NO.
NM-HU-241184
Strain State
Repository Live
Gene Summary
Gene Symbol
Pglyrp1
Model Description
Validation Data
Fig.1 Detection of PGLYRP1 expression in colon by RT-PCR. Mouse Pglyrp1 mRNA (249 bp) was detectable only in wild-type C57BL/6 mice. Human PGLYRP1 mRNA (207 bp) was detectable only in homozygous hPGLYRP1 knockin mice but not in wild-type mice. Colon RNA was extracted from 6-week-old female wild-type C57BL/6 (WT)(n=2) and homozygous hPGLYRP1 knockin mice (HO) (n=2), then cDNA libraries were synthesized by reverse transcription, followed by PCR with mRNA primers.
Abbr. M, marker; HO, homozygous; WT, wild type.
Fig.2 Detection of human PGLYRP1 expression in serum of WT C57BL/6 mice and HO hPGLYRP1 mice by ELISA. Human PGLYRP1 was exclusively detectable in serum from HO hPGLYRP1 mice. Serum were collected from wild-type C57BL/6 mice (n=2, male, 10 weeks old) and HO hPGLYRP1 mice (n=2, male, 10 weeks old), and analyzed by ELISA with anti-hPGLYRP1 ELISA kit.
Abbr. HO, homozygous; WT, wild type; N.D. not detected.
Fig.3 Detection of human PGLYRP1 expression in serum of WT C57BL/6 mice and HO hPGLYRP1 mice by ELISA. Human PGLYRP1 was exclusively detectable in serum from HO hPGLYRP1 mice. Serum were collected from wild-type C57BL/6 mice (n=2, female, 6 weeks old) and HO hPGLYRP1 mice (n=2, female, 6 weeks old), and analyzed by ELISA with anti-hPGLYRP1 ELISA kit.
Abbr. HO, homozygous; WT, wild type; N.D. not detected.
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