Abcb1a/Abcb1b-KO(SD)

Nomenclature

SD-Abcb1aemAbcb1bem1Smoc

Cat. NO.

NR-KO-241992

Strain State

Repository Live

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Gene Summary

Gene Symbol
Abcb1a

Synonyms

Abcb1; Mdr1a

NCBI ID

170913

RGD ID

619951

Ensembl ID

ENSRNOG00000008012

Pubmed

Abcb1a

Human Ortholog

-

Model Description

The exon 4 of Abcb1a and exon 4 of Abcb1b genes were deleted to generate Abcb1a and Abcb1b knockout rat.

Validation Data

image.png

Fig.1 Detection of ABCB1 expression in Abcb1a/Abcb1b-KO(SD) rat by WB. Rat ABCB1 was exclusively detectable in small intestine, brain and kidney from WT SD. The small intestine, brain and kidney tissue lysates were collected from 20-week-old male wild-type SD rat and 20-week-old male homozygous Abcb1a/Abcb1b-KO(SD) rat, and then analyzed by western blot. 

Abbr. HO, homozygous; WT, wild type; PC, positive control, PC1, HepG2 cells, PC2, Hela cells.


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