B2m-KO(NMG)
Nomenclature
NOD.Cg-PrkdcscidIl2rgem1SmocB2mem1Smoc
Cat. NO.
NM-NSG-002
Strain State
Repository Live
Gene Summary
Gene Symbol
B2M
Model Description
This B2m knockout mouse model was obtained by knocking out the exon 2-3 region of mouse B2m gene on the background of NMG mouse.
Validation Data
Fig1.Detection of MHCII and B2m expression in spleen in B2m-KO(NMG) mice by RT-PCR.
Abbr. M, DNA marker
Fig2. Expression characterization of mouse MHC I and MHC II in bone marrow, blood, spleen in B2m-KO(NMG) mice.
Fig 3. Body weight growth curve of huPBMC-B2m-KO(NMG) mice.
Fig 4. Survival rate of huPBMC-B2m-KO(NMG) mice.
Fig 5. GvHD scores of huPBMC-B2m-KO(NMG) mice.
Fig 6. Percentage of hCD45-positive cells of huPBMC-B2m-KO(NMG) mice.
Fig 7. Flow analysis of peripheral blood lymphocyte subpopulations in the huPBMC-B2m-KO(NMG) mice.
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