hCCR5
Nomenclature
C57BL/6JSmo-Ccr5tm1(hCCR5)Smoc
Cat. NO.
NM-HU-2000065
Strain State
Embryo cryopreservation
Gene Summary
Gene Symbol
Ccr5
Model Description
The endogenous mouse Ccr5 gene was replaced by human CCR5 gene.
Research Application：Immunotherapy,drug screening
*Literature published using this strain should indicate: hCCR5 mice (Cat. NO. NM-HU-2000065) were purchased from Shanghai Model Organisms Center, Inc..
Validation Data
Fig1. Analysis of CCR5 gene expression in the spleen by RT-PCR.
Mouse Ccr5 mRNA was detectable by P1/2(869bp), human CCR5 mRNA was detectable by P1/3(607bp),
M:100bp Plus DNA ladder from Transgen (BM311). The heterozygous KI mouse expresses both human CCR5 and mouse Ccr5 in the spleen.
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