Krt5-2A-CreERT2

Nomenclature

C57BL/6Smoc-Krt5em1(2A-CreERT2)Smoc

Cat. NO.

NM-KI-190016

Strain State

Sperm cryopreservation

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Gene Summary

Gene Symbol
Krt5

Synonyms

K5; CK5; Tfip8; Krt2-5; AW146334; 3300001P10Rik

NCBI ID

110308

MGI ID

96702

Ensembl ID

ENSMUSG00000061527

Pubmed

Krt5

Human Ortholog

KRT5

Model Description

The 2A-CreERT2 cassette is inserted before 3'UTR region of Krt5 gene.
Research Application：Cre recombinase tool

Validation Data

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Fig1. CreERT2 mediated recombination in skin of Krt5CreERT2/+; Rosa26tdTomato/+ mouse. 

krt5-2A-CREert2 5t,7.jpg

Fig2. Detection of tdTomato(red) in various tissues of Krt5CreERT2/+; Rosa26tdTomato/+ mouse. 

After tamoxifen induction, tdTomato was expressed in the eyeballs, lungs, salivary glands, stomach, kidneys, skin, and vagina.

Tissues with expression leakage in the uninduced group: eyeballs, salivary glands, stomach, kidneys, skin, and vagina. (35-days old, female) (For more detailed information please contact our technical advisor.) 

Publications 1piece

1. Generation of Vgll4‐DreER transgenic mouse for visualizingand manipulating VGLL4‐expressing cells in vivo
Published year：2023 References：WILEY

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