Vav1-2A-CreERT2

Nomenclature

C57BL/6Smoc-Vav1em1(2A-CreERT2-WPRE-pA)Smoc

Cat. NO.

NM-KI-233229

Strain State

Repository Live

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Gene Summary

Gene Symbol
Vav1

Model Description

The 2A-CreERT2-WPRE-pA expression cassette was knocked into the Vav1 gene stop codon site.

Validation Data

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Fig1. Cre mediated recombination in spleen of Vav1CreERT2/+; Rosa26tdTomato/+ mouse. 

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Fig2. Detection of tdTomato(red) in various tissues of Vav1CreERT2/+; Rosa26tdTomato/+ mouse. The tissues of double-positive mice were cryosectioned and directly examined, revealing expression in the following organs: spleen, thymus, spinal cord, lung, liver, stomach, salivary gland, brown fat, adrenal gland, kidney, pancreatic islet, small intestine, colon, testicular interstitium, skin, pituitary gland. A few cells expressed in heart, muscle. Non-expressed tissues included brain, retina. (43-days old, male) (For more detailed information please contact our technical advisor.) 



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