Flt3-2A-CreERT2

Nomenclature

C57BL/6Smoc-Flt3em1(2A-CreERT2)Smoc

Cat. NO.

NM-KI-231796

Strain State

Sperm cryopreservation

Export PDF

Gene Summary

Gene Symbol
Flt3

Model Description

The 2A-CreERT2 expression cassette was knocked into the Flt3 gene stop codon site.

Validation Data

image.png

Fig1. Cre mediated recombination in bone marrow of Flt3CreERT2/+;Rosa26tdTomato/+ mouse.  

image.png

Fig2. Detection of tdTomato(red) in various tissues of Flt3CreERT2/+;Rosa26tdTomato/+ mouse. Expression tissues include: lung, bone marrow, kidney, spleen and muscle. A few cells expressed in brain, liver, stomach, salivary gland, brown fat, adrenal gland, colon, testis, skin, thymus. Tissues that unexpressed include spinal cord, retina, heart, pancreas, small intestine and pituitary gland. (49-days old, male) (For more detailed information please contact our technical advisor.)


You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Workshop:Progress and Advances in Preclinical immuno-Oncology Research

SMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.

Learn more