Lgr5-2A-Dre

Nomenclature

C57BL/6Smoc-Lgr5em1(2A-Dre)Smoc

Cat. NO.

NM-KI-215042

Strain State

Sperm cryopreservation

Export PDF

Model Description

2A-Dre expression cassette was knocked into the Lgr5 gene.

Validation Data

image.png

Fig 1. Dre-mediated recombination in stomach of Lgr5Dre/+; Rosa26tdTomato/+ mice.

image.png

Fig 2. Detection of tdTomato (red) in various tissues of Lgr5Dre/+; Rosa26tdTomato/+ mice. Expression tissues include: olfactory bulb, spinal cord, retina, lung, liver, stomach, kidney, small intestine, large intestine, epididymis, skin, pituitary gland. A few cells expressed in salivary gland, brown fat, thymus, pancreas, testis, muscle, adrenal gland. Tissues that unexpressed include heart. (8.5-week old, male) (For more detailed information please contact our technical advisor.) 


You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Workshop:Progress and Advances in Preclinical immuno-Oncology Research

SMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.

Learn more