Ptf1a-CreERT2

Fig.1 CreERT2-mediated recombination in the pancreas of Ptf1a^CreERT2/+ ; Rosa26^tdTomato/+ mouse. 

TdTomato(red) expression can be detected in the pancreatic acinar cells of Ptf1a^CreERT2/+; Rosa26^tdTomato/+ mouse after tamoxifen treatment. 

Fig.2 Detection of tdTomato (red) in various tissues of Ptf1a^CreERT2/+; Rosa26^tdTomato/+ mice after tamoxifen treatment. 

CreERT2-mediated recombination in the pancreatic acinar cells  can be induced by tamoxifen. Some leakiness were detected in the pancreas prior to tamoxifen exposure. Besides, tdtomato expression can be detected in a few cells of the brain, pituitary gland and stomach. Tdtomato exprssion can not be detected in thymus, heart, lung, liver, testis, kidney, intestine, brown fat, spleen, submandibular gland, and muscle. (For more detailed information please contact our technical advisor.)