Nos1-CreERT2

Fig. 1 CreERT2-mediated recombination in the brian of Nos1^{CreERT2 /+}; Rosa26^tdTomato/+ mouse. TdTomato(red) expression can be detected in the NOS1 positive neurons of Nos1^{CreERT2 /+}; Rosa26^tdTomato/+ mouse after tamoxifen treatment. 

Fig. 2 CreERT2-mediated recombination in the large intestine of Nos1^{CreERT2 /+}; Rosa26^tdTomato/+ mouse. TdTomato(red) expression can be detected in the muscular layer of the wall of the large intestine derived from Nos1^{CreERT2 /+}; Rosa26^tdTomato/+ mouse after tamoxifen treatment. 

Fig. 3 CreERT2-mediated recombination in the small intestine of Nos1^{CreERT2 /+}; Rosa26^tdTomato/+ mouse. TdTomato(red) expression can be detected in the muscular layer of the wall of the small intestine derived from Nos1^{CreERT2 /+}; Rosa26^tdTomato/+ mouse after tamoxifen treatment.

Fig. 4 Detection of tdTomato(red) in various tissues of Nos1^CreERT2/+; Rosa26^tdTomato/+ mice. CreERT2 mediated recombination can be detected in some cells of the brain and intestine. Some leakiness were detected prior to tamoxifen exposure. Besides, tamoxifen-dependent cre recombinase expression can also be detected in some cells derived from eyes, lung, submandibular gland, kidney, spleen, thymus, muscle and ovary, except for heart, brown fat tissue and liver. (For more detailed information please contact our technical advisor.)