Eno2-2A-Cre

Nomenclature

C57BL/6Smoc-Eno2em1(2A-iCre)Smoc

Cat. NO.

NM-KI-200012

Strain State

Repository Live

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Gene Summary

Gene Symbol
Eno2

Synonyms

NSE; Eno-2; AI837106; D6Ertd375e

NCBI ID

13807

MGI ID

95394

Ensembl ID

ENSMUSG00000004267

Pubmed

Eno2

Human Ortholog

ENO2

Model Description

A 2A-iCre expression cassette was knocked into the Eno2 gene stop codon site.
Research Application：Eno2 is a highly specific marker for neuronal and peripheral neuroendocrine cells. This strain is useful in the study of human motor neuron diseases such as brain injury and spinal muscular atrophy.

Validation Data

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Fig. 1 Cre-mediated recombination in the brain of Eno2Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the neurons of Eno2Cre/+; Rosa26tdTomato/+ mouse. 

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Fig. 2 Cre-mediated recombination in the spinal cord of Eno2Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the neurons of Eno2Cre/+; Rosa26tdTomato/+ mouse. 

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Fig. 3 Detection of tdTomato(red) in various tissues of Eno2Cre/+; Rosa26tdTomato/+ mice. Tdtomato was expressed in the brain and spinal cord. TdTomato can also be detected in individual cells of the pitultary gland, testis, heart, lung, liver, stomach, submandibular gland, brown fat, kidney, pancreas, intestine, colon, spleen, thymus, muscle and skin. (For more detailed information please contact our technical advisor.)


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