Cpa3-2A-CreERT2

Nomenclature

C57BL/6JSmo-Cpa3em2(2A-CreERT2-WPRE-polyA)Smoc

Cat. NO.

NM-KI-200005

Strain State

Repository Live

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Gene Summary

Gene Symbol
Cpa3

Synonyms

MC-CPA

NCBI ID

12873

MGI ID

88479

Ensembl ID

ENSMUSG00000001865

Pubmed

Cpa3

Human Ortholog

CPA3

Model Description

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Cpa3 gene stop codon site.
Research Application：Cre recombinase tool

Validation Data

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Fig1. Cre mediated recombination in skin of Cpa3CreERT2/+;Rosa26tdTomato/+ mouse.

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Fig2. Cre mediated recombination in stomach of Cpa3CreERT2/+;Rosa26tdTomato/+ mouse.

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Fig3. Detection of tdTomato(red) in various tissues of Cpa3CreERT2/+;Rosa26tdTomato/+ mouse. Expression tissues include: skin and stomach. A few cells expressed in: salivary gland and uterus. No obvious positive signals were observed in the brain, pituitary gland, retina, heart, lungs, liver, brown fat, muscles, kidneys, pancreas, small intestine, large intestine, spleen and thymus.(61-days old, female) (For more detailed information please contact our technical advisor.)

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Fig4. Detection of mast cells in stomach and skin of Cpa3CreERT2/+;Rosa26tdTomato/+ mouse. No reduction in mast cells was observed in the skin of Cpa3CreERT2/+;Rosa26tdTomato/+ induced with Tamoxifen.

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