Krt14-CreERT2

Nomenclature

C57BL/6Smoc-Krt14em2(CreERT2-Wpre-polyA)Smoc

Cat. NO.

NM-KI-190024

Strain State

Repository Live

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Gene Summary

Gene Symbol
Krt14

Synonyms

K14; CK-14; Krt1-14; AI626930; Krt-1.14

NCBI ID

16664

MGI ID

96688

Ensembl ID

ENSMUSG00000045545

Pubmed

Krt14

Human Ortholog

KRT14

Model Description

A CreERT2-Wpre-polyA expression cassette was knocked into initiation codon ATG site of the Krt14 gene.
Research Application：Cre recombinase tool

Validation Data

微信截图_20190716101355.png

Fig1 CreERT2-mediated recombination in Skin, Tongue & Esophagus of Krt14 CreERT2+/-;R26 tdTomato+/- mice.

A， Krt14-CreERT2+/- ; Rosa26 tdTomato+/- ; Tamoxifen

B， Krt14-CreERT2+/-; Rosa26 tdTomato+/- 

C， Rosa26 tdTomato+/-


微信截图_20190716101755.png

Fig2 Confocal images showing expression of tdTomato in Skin, Tongue & Esophagus of Krt14 CreERT2+/-;R26 tdTomato +/- mice.

A， Krt14-CreERT2+/- ; Rosa26 tdTomato+/- ; Tamoxifen

B， Krt14-CreERT2+/-; Rosa26 tdTomato+/- 

C， Rosa26 tdTomato+/-

Publications 2piece

1. Pharmacological inhibition of MYC to mitigate chemoresistance in preclinical models of squamous cell carcinoma
Published year：2024-01-01 References：Theranostics

2. A novel lineage of osteoprogenitor cells with dual epithelial and mesenchymal properties govern maxillofacial bone homeostasis and regeneration after MSFL
Published year：2022-07-12 References：Cell Research

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