Npr3-2A-DreERT2

Nomenclature

C57BL/6Smoc-Npr3em1(2A-DreERT2)Smoc

Cat. NO.

NM-KI-190015

Strain State

Sperm cryopreservation

Export PDF

Gene Summary

Gene Symbol
Npr3

Synonyms

lgj; EF-2; stri; ANP-C; NPR-C; ANPR-C

NCBI ID

18162

MGI ID

97373

Ensembl ID

ENSMUSG00000022206

Pubmed

Npr3

Human Ortholog

NPR3

Model Description

The 2A-DreERT2 cassette is inserted before 3'UTR region of Npr3 gene.
Research Application：Dre recombinase tool

Validation Data

image.png

Fig.1 DreERT2-mediated recombination in the heart of Npr3DreERT2/+；R26ZsGreen/+ mouse. ZsGreen (green) expression can be detected in the heart after tamoxifen treatment. Fabp4 (tdTomato) is the marker gene known to be expressed in the coronary vessel endothelial cells. (Documented in the following reference.)


Publications 1piece

1. A Suite of New Dre-recombinase Drivers Markedly Expands the Ability to Perform Intersectional Genetic Targeting
Published year：2021-02-09 References：CELL STEM CELL

展开

You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Workshop：Progress and Advances in Preclinical immuno-Oncology Research

SMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.

Learn more