Rb1-Flox/Trp53-Flox/R26-CAG-LSL-Luc-2A-EGFP
Strain Information
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Cre-ERT2在无Tamoxifen诱导的情况下,在细胞质内处于无活性状态;当Tamoxifen诱导后,Tamoxifen的代谢产物4-OHT(雌激素类似物)与ERT结合,可使Cre-ERT2进核发挥Cre重组酶活性。
Learn moreCell Line
Rb1-Flox/Trp53-Flox/R26-CAG-LSL-Luc-2A-EGFP
Cat. NO.
NM-YD16
Model Description
Derived from Rb1-Flox/Trp53-Flox/R26-CAG-LSL-Luc-2A-EGFP mice(NM-KI-234513) spontaneous lung cancer model
Strain State
Construction
Cre-ERT2在无Tamoxifen诱导的情况下,在细胞质内处于无活性状态;当Tamoxifen诱导后,Tamoxifen的代谢产物4-OHT(雌激素类似物)与ERT结合,可使Cre-ERT2进核发挥Cre重组酶活性。
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