R26-CAG-loxp-tdTomato-loxp2272-Tag-IRES-EGFP-2A-Luc-loxp-loxp2272/Alb-Cre-Tg
Strain Information
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Cre-ERT2在无Tamoxifen诱导的情况下,在细胞质内处于无活性状态;当Tamoxifen诱导后,Tamoxifen的代谢产物4-OHT(雌激素类似物)与ERT结合,可使Cre-ERT2进核发挥Cre重组酶活性。
Learn moreCell Line
R26-CAG-loxp-tdTomato-loxp2272-Tag-IRES-EGFP-2A-Luc-loxp-loxp2272/Alb-Cre-Tg
Cat. NO.
NM-YD14
Model Description
Derived from R26-CAG-loxp-tdTomato-loxp2272-Tag-IRES-EGFP-2A-Luc-loxp-loxp2272/Alb-Cre-Tg mice spontaneous liver cancer model
Strain State
Construction
Cre-ERT2在无Tamoxifen诱导的情况下,在细胞质内处于无活性状态;当Tamoxifen诱导后,Tamoxifen的代谢产物4-OHT(雌激素类似物)与ERT结合,可使Cre-ERT2进核发挥Cre重组酶活性。
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