hB4GALNT1

Nomenclature

C57BL/6Smoc-B4galnt1em1(hB4GALNT1)Smoc

Cat. NO.

NM-HU-220337

Strain State

Repository Live

Export PDF

Gene Summary

Gene Symbol
B4galnt1

Model Description

The endogenous mouse B4galnt1 gene was replaced by human B4GALNT1 gene.

Validation Data

image.png

Fig.1 Detection of B4GALNT1 expression in duodenum by RT-PCR. Duodenum RNA was extracted from 12-year-old male wild-type C57BL/6 (WT)(n=3) and homozygous hB4GALNT1 knockin mice (HO) (n=3), then cDNA libraries were synthesized by reverse transcription, followed by PCR with mRNA primers. Mouse B4galnt1 mRNA (261 bp) was detectable only in wild-type C57BL/6 mice. Human B4GALNT1 mRNA (235 bp) was detectable only in homozygous hB4GALNT1 knockin mice but not in wild-type mice. 


You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Workshop:Progress and Advances in Preclinical immuno-Oncology Research

SMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.

Learn more