hLY96

Nomenclature

C57BL/6JSmo-Ly96tm1(hLY96)/Smoc

Cat. NO.

NM-HU-210003

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Ly96

Model Description

The endogenous mice Ly96 gene was replaced by human LY96 gene
Research Application:drug screening

Validation Data

image.png

Fig.1 Detection of LY96 expression in bladder by RT-PCR. 

Wild type: only one band at 254 bp with primers F1/R1(mLy96);

Homozygous: only one band at 269 bp with primers F2/R2(hLY96); 

Abbr. M, DNA marker; HO, homozygous; WT, wild type.image.png

Fig.2 Detection of hLY96 expression in liver homogenate by ELISA (n=3). 

Abbr. HO, homozygous; WT, wild type.

Note. hLY96 and C57BL/6 mice were i.p. injected with LPS.

The human LY96 ELISA kit cross-reacted with mLY96 and humanized LY96.


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