Knockout mouse model is a laboratory mouse in which researchers have inactivated, or "knocked out," an existing gene by deleting portions of the gene’s DNA sequence, or by replacing the gene with an altered DNA sequence. Knockout mice exhibit modifications in phenotype (observable traits) and thereby provide important clues about the function of individual genes. Mice and humans share many genes in common. Hence, information from knockout mouse models can shed light on the biological roles of specific genes as well as on the involvement of those genes in human disease.
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Strain Name：C57BL/6Smoc-Agpat2em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-201122
Disease Connection：congenital generalized lipodystrophy type 1
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Strain Name：C57BL/6Smoc-Agpat4em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-234999
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Strain Name：C57BL/6Smoc-Agpat5em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-231490
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Strain Name：C57BL/6Smoc-Agpsem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-2105835
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Strain Name：C57BL/6Smoc-Agr2em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-210332
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Strain Name：C57BL/6Smoc-Agr3em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190237
Research Application：Immune-related
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Strain Name：C57BL/6Smoc-Agrpem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190636
Research Application：late on-set obesity
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Strain Name：B6.129S-Agtr1atm1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-00041
Research Application：cardiovascular system,nervous system
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Strain Name：C57BL/6Smoc-Agtem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190740
Research Application：This gene is associated with susceptibility to essential hypertension, non-familial structural atrial fibrillation, and inflammatory bowel disease.
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