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Models

Inducible Cell Ablation

Inducible cell ablation mouse models express DTR molecules under the control of elements from cell-specific genes. The targeted cells will be deleted after diphtheria toxin (DT) treatment. Such systems enable the studies of the function of immune cells.

mouse
Itgam-IRES-DTRGFP
Strain Name：C57BL/6JSmo-Itgamem1(IRES-DTR-EGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200066
Research Application：DTR mouse of macrophages
mouse
Itgax-2A-tdTomato-2A-DTR
Strain Name：C57BL/6JSmo-Itgaxem(T2A-tdTomato-P2A-DTR)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-204992
mouse
Karma-2A-tdTomato-2A-DTR
Strain Name：C57BL/6JSmo-Gpr141bem1(2A-tdTomato-2A-DTR)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-210116
Research Application：DTR tool mice
mouse
Ly6g-2A-DTRGFP(BALB/c)
Strain Name：BALB/cJSmo-Ly6gem(2A-DTRGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-204997
mouse
Lyz2-IRES-DTRGFP
Strain Name：C57BL/6JSmo-Lyz2em3(IRES-DTREGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190041
Research Application：DTR mouse
mouse
Ncr1-IRES-DTRGFP
Strain Name：
Strain State： | Cat. NO.：
mouse
Ncr1-IRES-DTRGFP(BALB/c)
Strain Name：BALB/cJSmo-Ncr1em1(IRES-DTREGFP)Smoc
Strain State：Developing | Cat. NO.：NM-KI-200180
Research Application：DTR mouse
mouse
Pdcd1-DTR-2A-tdTomato
Strain Name：C57BL/6JSmo-Pdcd1em1(DTR-2A-tdTomato-WPRE-pA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200225
Research Application：DTR tool mice
mouse
R26-CAG-LSL-hTARDBP*A315T-EGFP
Strain Name：C57BL/6JSmo-Gt(ROSA)26Sortm1(CAG-LSL-3xFlag-TARDBP(A315T)-IRES-GFP-WPRE-PA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200019
Research Application：Amyotrophic lateral sclerosis(ALS) and frontotemporal lobar degeneration research
mouse
R26-CAG-LSL-hTM6SF2*E167K-EGFP
Strain Name：C57BL/6JSmo-Gt(ROSA)26Sortm1(SA-Frt-2xpolyA-CAG-Frt-LSL-TM6SF2-IRES-GFP-WPRE-PA)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200017
Research Application：Non-alcoholic fatty liver disease
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