hB7H3/hCD28

Nomenclature

C57BL/6Smoc-Cd276tm2(hCD276)Cd28em2(hCD28)Smoc

Cat. NO.

NM-HU-210353

Strain State

Embryo cryopreservation

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Model Description

hB7-H3(NM-HU-00107) was crossed with hCD28(NM-HU-190011) to generate hB7H3/hCD28 mice.
Research Application：inmmue therapy；drug screening

Validation Data

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Fig1. Detection of B7H3 expression in liver and spleen by RT-PCR. Wild type: only one band at 365 bp with primers F1/R1(mB7h3);Homozygous: only one band at 225 bp with primers F2/R2(hB7H3); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig2. Detection of CD28 expression in liver and spleen by RT-PCR. Wild type: no band with primers F2/R2(hCD28);Homozygous: only one band at 201 bp with primers F2/R2(hCD28); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

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