SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Tnfrsf4em3(hTNFRSF4) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00108
Research Application：cancer research,Immunotherapy,drug screening
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Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00100
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd274em2(hPD-L1)Ccr8em1(hCCR8)/Smoc
Strain State：Developing | Cat. NO.：NM-HU-210402
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Strain Name：BALB/cAnSmoc-Pdcd1em(hPDCD1)Cd274em(hPD-L1)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220142
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Strain Name：BALB/cAnSmoc-Pdcd1em(hPDCD1)Cd274em(hPD-L1)Sirpatm4(hSIRPA)Cd47em1(hCD47)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220143
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Strain Name：C57BL/6Smoc-Pdcd1em1(hPD-1)Cd274em1(hPD-L1)Nt5eem2(hNT5E)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210410
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Strain Name：C57BL/6Smoc-Pdcd1em1(hPD-1)Cd274em1(hPD-L1)Ctla4em1(hCTLA4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200266
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Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Lag3em1(hLAG3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190028
Research Application：Immune-related
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Strain Name：C57BL/6Smoc-Tnfrsf4em3(hTNFRSF4)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00122
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Pdcd1lg2em1(hPDCD1LG2)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190060
Research Application：Immunotherapy,cancer research,drug screening
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