hIL17RA(BALB/c)

Nomenclature

BALB/cAnSmoc-Il17ratm1(hIL17RA)Smoc

Cat. NO.

NM-HU-220015

Strain State

Repository Live

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Gene Summary

Gene Symbol
IL17RA

Model Description

The endogenous mouse Il17ra gene was replaced by human IL17RA gene.

Validation Data

image.png

Fig1. Detection of IL-17RA expression in thymus and spleen by RT-PCR. 

Wild type: only one band at 327 bp with primers F1/R1(mH2-k1);Heterozygous: one band at 327 bp with primers F1/R1(mH2-k1) and one band at 364 bp with primers F2/R2(hIL-17RA); 

Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig.2 Detection of IL17RA expression by FACS. 

The expression of mouse and human IL17RA were analyzed in splenic myeloid cells from 9-week-old male WT and 14-week-old male hIL17RA knockin mice.

Abbr. HO, homozygous; WT, wild type.


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