hIL15RA

Nomenclature

C57BL/6JSmo-Il15ratm1(hIL15RA)Smoc

Cat. NO.

NM-HU-215070

Strain State

Repository Live

Export PDF

Gene Summary

Gene Symbol
Il15ra

Model Description

The endogenous mouse Il15ra gene was replaced by human IL15RA gene.

Validation Data

image.png

Fig.1 Detection of hIL15RA expression on DC cells and Macrophage in BM of WT C57BL/6 mice and HO hIL15RA mice by FACS. hIL15RA was exclusively detectable in hIL15RA humanized mice but not in wild-type mice. hIL15RA was exclusively detectable on DC cells and Macrophage in hIL15RA humanized mice. Leukocytes were collected from wild-type C57BL/6 mice (male, 6 weeks old) and homozygous HO hIL15RA humanized mice (male, 6 weeks old),stimulated with LPS in vitro(1ug/ml), and analyzed by flow cytometry with anti-mIL15RA , anti-hIL15RA.

Abbr. HO, homozygous; WT, wild type.


You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more

Workshop:Progress and Advances in Preclinical immuno-Oncology Research

SMOC’s Annual Progress and Advances in Preclinical immuno-Oncology Research: The workshop is designed as a forum for ideas and opinions exchange on how to decrease the rate of clinical failures in oncology and immuno-oncology.

Learn more

Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

Learn more