hAXL

Nomenclature

C57BL/6Smoc-Axltm1(hAXL)Smoc

Cat. NO.

NM-HU-215067

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
AXL

Synonyms

ARK; UFO; JTK11; Tyro7

NCBI ID

558

MGI ID

Null

Ensembl ID

ENSG00000167601

Pubmed

AXL

Human Ortholog

AXL

Model Description

The endogenous mouse Axl gene was replaced by human AXL gene.

Validation Data

image.png

Fig1. Detection of AXL expression in lung and spleen by RT-PCR. 

Wild type: only one band at 202 bp with primers F1/R1(mAxl); Homozygous: only one band at 249 bp with primers F2/R2(hAXL). Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig2. Detection of human AXL expression in liver in hAXL knockin mice by WB. 

Livers were collected from wild-type mice (+/+) and homozygous hAXL mice (HO/HO), and analyzed by western blot with anti-AXL antibody. Abbr. HO/HO, homozygous; +/+, wild type.

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