hGPRC5D

Nomenclature

C57BL/6Smoc-Gprc5dtm1(hGPRC5D)Smoc

Cat. NO.

NM-HU-215058

Strain State

Repository Live

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Gene Summary

Gene Symbol
Gprc5d

Model Description

The endogenous mouse Gprc5d gene was replaced by human GPRC5D gene.

Validation Data

image.png

Fig.1 Detection of GPRC5D expression in mammary gland and liver of 9-week-old female WT and hGPRC5D mice by RT-PCR. 

Wild type: only one band at 253 bp with primers F1/R1(mGprc5d);

Homozygous:  only one band at 409 bp with primers F2/R2(hGPRC5D).

Abbr. M, DNA marker; HO, homozygous; WT, wild type.

image.png

Fig.2 Detection of human GPRC5D expression in 9-week-old female WT and hGPRC5D knockin mice by WB. 

Abbr. M, marker; WT, wild type; HO, Homozygous.

Note. The anti-human GPRC5D antibody cross-reacted with mouse GPRC5D and humanized GPRC5D.


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