hCD44

Nomenclature

C57BL/6Smoc-Cd44tm(hCD44)Smoc

Cat. NO.

NM-HU-215003

Strain State

Repository Live

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Gene Summary

Gene Symbol
Cxcr5

Synonyms

Blr1; Gpcr6; MDR15; CXC-R5; CXCR-5

Chromosome

9

NCBI ID

12145

MGI ID

103567

Ensembl ID

ENSMUSG00000047880

Pubmed

Cxcr5

Human Ortholog

CXCR5

Model Description

The endogenous mice Cd44 gene was replaced by human CD44 gene.

Validation Data

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Fig1. Detection of CD44 expression in spleen and lung by RT-PCR. Wild type: only one band at 213 bp with primers F1/R1(mCd44);Heterozygous: one band at 213 bp with primers F1/R1(mCd44) and one band at 442 bp with primers F2/R2(hCD44); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

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Fig2. Expression characterization of hCD44 on MOLM-16 cell line.

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Fig3. Expression characterization of hCD44 in Blood in hCD44 KI mice.

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Fig4. Expression characterization of hCD44 in Spleen in hCD44 KI mice.

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Fig5. Expression characterization of hCD44 in Bone Marrow in hCD44 KI mice.

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